![]() A medication wouldn’t be recommended to lower BUN levels. A low-protein diet can also help lower BUN levels. Proper hydration is the most effective way to lower BUN levels. General reference ranges for a normal BUN level are as follows: Adults up to 60 years of age: 6-20 mg/dL. Needing to go the bathroom (urinate) frequently or infrequently.In addition, your BUN levels may be checked if you are experiencing symptoms of later stage kidney disease, such as: What are the symptoms of high BUN levels? Other possible causes of an elevated BUN include dehydration and heart failure. If your BUN is more than 20 mg/dL, your kidneys may not be working at full strength. Normal blood contains 7-20 mg/dl of urea. If your kidneys are not working well, the urea nitrogen will stay in the blood. What level of BUN indicates kidney failure? ![]() Urea nitrogen levels tend to increase with age. But normal ranges may vary, depending on the reference range used by the lab and your age. In general, around 6 to 24 mg/dL (2.1 to 8.5 mmol/L ) is considered normal. For permission to use (where not already granted under a licence) please go to. ![]() Published by the BMJ Publishing Group Limited. CLINICAL TRIALS: gov identifier NCT00328692 and NCT00354458. In patients with AHF, BUN/creatinine higher than age-specific and sex-specific normal range is associated with worse prognosis independently from both creatinine and BUN. In Cox regression analysis, higher than normal range of BUN/creatinine ratio group was an independent predictor for all-cause death (HR: 1.86, 95% CI 1.29 to 2.66) and death or cardiovascular or renal rehospitalisation (HR: 1.37, 95% CI 1.03 to 1.82), but not for HF rehospitalisation (HR: 1.23, 95% CI 0.81 to 1.86) after adjustment for other prognostic factors including both creatinine and BUN. In a cohort of patients with AHF, 482 (24.6%) and 28 (1.4%) patients with HF were classified into higher and lower than normal range groups, respectively. Association of abnormal range to prognosis was tested in 2033 patients with AHF for the outcome of all-cause death through 180 days, death or cardiovascular or renal rehospitalisation through 60 days and heart failure (HF) rehospitalisation within 60 days. In 4484 subjects from the general population without cardiovascular comorbidities, we calculated age-specific and sex-specific normal values of the BUN/creatinine ratio, deriving a higher and lower than normal range of BUN/creatinine ratio (exceeding the 95% prediction intervals). The aim of this study is to define the normal range of BUN/creatinine ratio and to investigate its clinical significance in patients with AHF. The blood urea nitrogen-to-creatinine (BUN/creatinine) ratio has been proposed as a useful parameter in acute heart failure (AHF), but data on the normal range and the added value of the ratio compared with its separate components in patients with AHF are lacking. 13 Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.12 Top Institute Food and Nutrition, Wageningen, The Netherlands.11 Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.10 University of Iowa Carver College of Medicine Cardiovascular Research Center, Iowa City, Iowa, USA.9 Merck Research Laboratories, Rahway, New Jersey, USA.8 Brigham and Women's Hospital, Boston, Massachusetts, USA.7 National Heart and Lung Institute, Royal Brompton and Harefield Hospitals, Imperial College, London, UK.6 Momentum Research, Durham, North Carolina, USA.5 San Francisco Veterans Affairs Medical Center, University of California San Francisco, San Francisco, California, USA. ![]()
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